Testosterone Replacement Therapy TRT Hormone

by Dr. Randy Smith of Antiaging Atlanta



TRT or Testosterone Replacment Therapy May Not Be Factor In BPH or LUTS, Low Testosterone Level May Actually Be Causing Benign Prostatic Hypertrophy and Lower Urinary Tract Symptoms



2016 Jun;17(6):46. doi: 10.1007/s11934-016-0600-8.

Testosterone Replacement Therapy and BPH/LUTS. What is the Evidence?


Contrary to the previous dogma that prostatic growth is directly proportional to testosterone levels, emerging research has suggested a lack of testosterone may be a risk factor for lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). Within this review article, we have demonstrated the current understanding of the physiology of hypogonadism and its interplay with prostatic and lower urinary tract physiology. The current evidence suggests that not only does testosterone replacement therapy (TRT) not worsen LUTS, but that hypogonadism itself is an important risk factor for LUTS/BPH.


Benign prostatic hyperplasia; Lower urinary tract symptoms; Testosterone replacement therapy

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